Couple of references here on antihistamines, if anyone's interested:
CSACI position statement: Newer generation H1-antihistamines are safer than first-generation H1-antihistamines and should be the first-line antihistamines for the treatment of allergic rhinitis and urticaria - Allergy, Asthma & Clinical Immunology
Oral H1-antihistamines (AHs) are the most commonly used therapy to treat allergic rhinitis and chronic urticaria. Older, first-generation AHs (e.g. diphenhydramine, hydroxyzine) have significant and common side effects including sedation, impairment with decreased cognitive function, poor sleep...
aacijournal.biomedcentral.com
Antihistamines: first generation vs newer antihistamines
AAAAI's Ask the Expert talks about antihistamines: if/when are first generation medications advantageous over newer antihistamines?
www.aaaai.org