I'll add my 2 cents in a bit. From the sounds of things, I might be a touch contrarian. (Sp?)
edit: I've gone back and forth on this one. If I'm using wire, I just use Beadalon 49 black .018", but I lean towards fluoro (I just catch more fish with it). a harder fluoro like Seaguar AbrazX. I can get away with 50lb, or even something like a mason hard mono in 40lb (could probably even get away with 25lb on that). At some point, with anything but 40+lb wire, you'll get bitten off, I haven't yet and I've put a whole bunch of tigers in the net over the last ~7-8 years. The thing you've gotta remember is that muskies and pike teeth aren't serrated, so they're not slicing things, but if the point comes down right in the middle of your tippet, that's how you get bite offs. Bottom line though, not all fluoro is created equal. You could use 80lb Red Label and it'll get bitten through easier than the 25lb Mason Hard Mono or the 40-50lb AbrazX.
It should also be noted that every single one of my flies have the barbs crimped. They typically come right out in the net.
Regarding clips, I've used the fastach clips and they work well except occasionally they'll get stuck in one position. That's why I stopped using them because you only get so many opportunities and I don't want that to fuck things up, so I just pre-rig all of my flies with ~12" of bite and loop to loop it to my leader (~4' of 30 or 40lb with a 75lb barrel swivel in the middle).